Prof. Hwang Woo-suk says he did make stem cells tailored to individual
patients, as claimed in his May paper in Science, and has the source
technology to keep making them, but he belatedly admitted to making
plenty of mistakes born out of negligence. At the same time, he says,
the team is withdrawing the Science article because damage from the
scandal is too extensive. The previous day, a collaborator of Hwang��s
and MizMedi Hospital board chairman Roh Sung-il said none of Hwang��s
embryonic stem cells exist, charging that Hwang will not admit it
because he is too attached to the project. Where the two agree is in saying that though Hwang and his team
did make six stem cells matching patients' DNA late last year and early
this year, they died of fungal contamination. Stem cells Nos. 2 and 3,
however, were sent to and kept at MizMedi before they could become
contaminated and later returned to Seoul National University. There,
the pictures and DNA fingerprints of the two stem cells were multiplied
to make them look like the 11 stem cells the article in Science
describes. Another five stem cells were not cloned from somatic cells but
taken from frozen embryos at MizMedi, Roh says. Hwang, meanwhile, says
errors in the DNA analysis of stem cells 2 and 3 are due to the fact
that someone mixed them up with frozen stem cells from MizMedi, an
allegation he is asking judicial authorities to investigate. We have no means of knowing who is telling the truth ? Hwang,
the Science paper��s first author, or Roh, its second. What is certain
is only that the pictures and DNA fingerprints of embryonic stem cells
published in Science are either not those of cloned stem cells at all
or were duplicated from a few. Under such circumstances, it will be
difficult for Hwang to find acceptance in the scientific community for
his claim to have the source technology. Now, over 70 experts from Seoul National University Veterinary
College and Medical School as well as from MizMedi took part in the
Hwang team��s research. Scientific circles and the government will have
to ask themselves why a paper is being questioned at such an elementary
level despite having been checked and supervised by so many experts in
advance. The stem cell project was initiated by Prof. Hwang on his own.
It grew into a state project with government backing and then became
the people's project, adding a massive weight of national expectation.
That very fact simply short-circuited any stringent verification
procedures by scientists and the government. Scientists kept mum
because they saw hope in one of their own becoming a national hero, and
the government was happy to bask in reflected glory without asking too
many questions. Between them, they immobilized the cool, rational
process of scientific enquiry.
The government will not be able to dodge its responsibility for
having failed to endure proper supervision of the research process
despite its pouring billions of taxpayers�� won into the project. When
President Roh Moo-hyun visited Hwang's laboratory, he said he hadn��t
been so moved since he took office. The prime minister visited Hwang's
dairy farm to promise official support; Cabinet ministers and other
politicians were so keen to be seen backing Hwang that they set up a
supporters club. The presidential secretary for science and technology, who
lists his name as a co-author of Prof. Hwang's 2004 paper on stem cells
cloned from somatic cells, formed a Hwang support group dubbed the
"Golden Bat" along with the presidential policy aide and the
information and communications minister. Quite a few people who
invested in bioengineering trusting the authorities�� assurances that
Hwang��s research would create tremendous national wealth are now
greatly perplexed. The media, admittedly, also transmitted Hwang��s every
assertion more or less unfiltered, using terms like "the people's
project" to embrace everything he did. By sanctifying Hwang, there is
no doubt that the press is partly responsible for making scientific
scrutiny difficult. Many have been hurt in the controversy. People who either
defended or criticized Hwang have had to put up with abuse from the
other side. But it is Korean science that has been hurt most, because
the international scientific community will from now on take any paper
written by a Korean scientist with a hefty pinch of salt. Still, the fact that one report was fabricated does not
invalidate the country��s claim to having reached world standard in the
field. What we need now are scientists determined to sort truth from
falsehood and turn this crisis into an opportunity for a new leap
forward, and a public that supports their effort. If our nation��s hopes
are ever to regain the height from which they plummeted when the stem
cell controversy struck, our scientists must first be able to walk tall
again.
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