More of the ground-breaking achievements of embattled cloning pioneer
Hwang Woo-suk have come under suspicion after the scientist admitted
fabricating data for a groundbreaking paper on stem cell research
published in Science in May this year. The Biological Research Information Center of Korea (BRIC) argues
on its websites that a photograph of stem cells accompanying a 2004
paper by Hwang is identical to one illustrating an article on stem cell
cultivation from fertilized embryos written by Kim Sun-jong and MizMedi
Hospital research staff, which was published in Stemcells magazine in
November 2004. Kim is a former member of Hwang��s stem cell research team, and
the head of MizMedi Hospital is a former collaborator whose name
appeared right next to Hwang��s on the May 2005 paper. BRIC claims Hwang
took a picture of the same stem cell from a different angle. Hwang��s
2004 paper serves as the basis for the Science article on
patient-specific stem cells. BRIC scientists also point out problems with DNA fingerprints
and the timing of stem cell cultivation, quoting Hwang as saying on
June 7, 2004 that only two cell clusters survived an unexpected
blackout in his lab in the fall of 2003, although he posted the 2004
paper in December 2003. That was not enough time to cultivate stem cells from the two
remaining clusters, the scientists say, since stem cells take at least
three months to cultivate. The overseas press has also raised
suspicions about the DNA fingerprints in the 2004 paper. Doubts are also spreading to what is ostensibly the world��s
first cloned dog Snuppy. Japan��s Yomiuri Shimbun on Monday quoted
geneticist Robert Lanza as saying he had proof of scientific errors in
Hwang��s paper on the cloning of the dog. Lanza proposed comparing the
original dog with the clone to confirm Hwang��s claim. Lanza is one of eight international scientists who recently
wrote to Science urging Hwang to help verify research results. A
professional rival, he works with bioengineering company Advanced Cell
Technology. A BRIC member said there were no DNA fingerprints in
Hwang��s paper showing that the original and cloned dogs were
genetically identical. The avalanche unleashed by Hwang��s admission on Friday also
threatens to sweep away the cow Youngrongi, which Hwang claims to have
cloned. Scientists now point out that the cow is said to have been
healthy and given birth to a calf since it was born in 1999. But cloned
animals are weaker than ordinary ones, and most are short-lived and
lack the ability to reproduce, they said. Hwang published no paper on
Youngrongi. ([email protected] )
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